Varenicline Impurity C03 CAS 230615-52-8
| CAS No. | 230615-52-8 |
| Molecular Formula | C11H13N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Varenicline Impurity C03.
As a process- or degradation-related impurity, Varenicline Impurity C03 (CAS 230615-52-8, C11H13NHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Varenicline Impurity C03 (C11H13NHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Varenicline Impurity C03 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13N HCl |
| Molecular Weight | 195.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2022 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Varenicline Standards
- Varenicline Impurity 28 (CAS 1026685-55-1)
- Varenicline Impurity 6 (CAS 116601-09-3)
- Varenicline Impurity 22 (CAS 1213781-59-9)
- Varenicline Impurity 31 (CAS 1333145-89-3)
- Varenicline Impurity 16 (CAS 1337563-47-9)
- Varenicline Impurity 70 (CAS 1337563-47-9 (free base))
- Varenicline Impurity 23 (CAS 1350219-74-7)
- Varenicline-d4 (CAS 2183239-01-0)
Recommended Standards
- Dotinurad Impurity 167 (CAS CATO-C4X-2494167)
- Zidovudine Impurity F (CAS 16053-52-4)
- Imrecoxib Impurity 13 (CAS 1338083-52-5)
- 3-(1H-Pyrrole-2-carboxamido)propanoic acid (CAS 129053-84-5)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (CAS 1491157-36-8)
- Trifluoro-methanesulfonic acid (1,1-dimethylbutyl)bis(1-methylethyl)silyl ester (CAS 1026271-34-0)
- 4-(Difluoromethyl)-2,6-difluoro-3-nitropyridine (CAS 1803673-08-6)
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- Des-Ala28-Tirzepatide (CAS CATO-CPTD788945)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com