8-chloro-3-(trifluoromethyl)imidazo[1,5-a]pyrazine CAS 2306263-43-2
| CAS No. | 2306263-43-2 |
| Molecular Formula | C7H11ClF3N3 |
| Molecular Weight | 229.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-chloro-3-(trifluoromethyl)imidazo[1,5-a]pyrazine (C7H11ClF3N3) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
8-chloro-3-(trifluoromethyl)imidazo[1,5-a]pyrazine (CAS 2306263-43-2), molecular formula C7H11ClF3N3 and molecular weight 229.63 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-chloro-3-(trifluoromethyl)imidazo[1,5-a]pyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H11ClF3N3 |
| Molecular Weight | 229.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- 2-chloro-1-[3-(trifluoromethyl)piperidin-1-yl]ethan-1-one (CAS 1183080-15-0)
- 4-chloro-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1256802-09-1)
- 6-chloro-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1256835-72-9)
- 4-chloro-6-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 1347759-36-7)
- 2-Chloro-1-(4-(trifluoromethyl)piperidin-1-yl)ethan-1-one (CAS 1482565-56-9)
- 5-chloro-3-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 1638768-23-6)
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