2-Chloro-3,3,3-trifluoro-1-(piperidin-1-yl)propan-1-one CAS 65388-63-8
| CAS No. | 65388-63-8 |
| Molecular Formula | C8H11ClF3NO |
| Molecular Weight | 229.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-3,3,3-trifluoro-1-(piperidin-1-yl)propan-1-one (C8H11ClF3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-Chloro-3,3,3-trifluoro-1-(piperidin-1-yl)propan-1-one (CAS 65388-63-8), a certified reference material (molecular formula C8H11ClF3NO, MW 229.63 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-3,3,3-trifluoro-1-(piperidin-1-yl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11ClF3NO |
| Molecular Weight | 229.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-chloro-1-[3-(trifluoromethyl)piperidin-1-yl]ethan-1-one (CAS 1183080-15-0)
- 4-chloro-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1256802-09-1)
- 6-chloro-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1256835-72-9)
- 4-chloro-6-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 1347759-36-7)
- 2-Chloro-1-(4-(trifluoromethyl)piperidin-1-yl)ethan-1-one (CAS 1482565-56-9)
- 5-chloro-3-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 1638768-23-6)
- 5-chloro-2-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine (CAS 40851-96-5)
- 8-chloro-3-(trifluoromethyl)imidazo[1,5-a]pyrazine (CAS 2306263-43-2)
Recommended Standards
- 4-(5-Chloro-3-fluoropyridin-2-yl)piperazin-2-one (CAS 1125426-55-2)
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- 5-(Chloromethyl)-3-(4-fluorophenyl)oxazolidin-2-one (CAS 1204297-74-4)
- (2-Chloro-4-fluorophenyl)(3-hydroxyazetidin-1-yl)methanone (CAS 1343974-68-4)
- 6-amino-7-fluoro-1H-quinoxalin-2-one (CAS 2758437-85-1)
- Prallethrin (CAS 23031-36-9)
- 2-Acetyl-3-methylpyridine (CAS 85279-30-7)
- 3-(2,4-Dichlorophenyl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 129177-17-9)
- Tizoxanide β-D-glucuronide, >98% (CAS 296777-75-8)
- 2-(4-Fluorophenyl)-N-(4-(thiophen-2-yl)thiazol-2-yl)acetamide (CAS 922576-52-1)
- Methyl 1-propyl-1h-pyrazole-5-carboxylate (CAS 1170869-49-4)
- 1,3,5-Trimethylpiperidin-4-one (CAS 824-31-7)
- 5-Bromo-1H-pyrazolo[3,4-c]pyridazine (CAS 1352546-83-8)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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