4-chloro-6-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine CAS 1347759-36-7
| CAS No. | 1347759-36-7 |
| Molecular Formula | C7H11ClF3N3 |
| Molecular Weight | 229.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 229.63 g/mol gives 4-chloro-6-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-chloro-6-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (CAS 1347759-36-7) is a high-purity analytical reference standard with the molecular formula C7H11ClF3N3 and a molecular weight of 229.63 g/mol.
The molecular framework of 4-chloro-6-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine (C7H11ClF3N3) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-chloro-6-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H11ClF3N3 |
| Molecular Weight | 229.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
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- 6-chloro-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1256835-72-9)
- 2-Chloro-1-(4-(trifluoromethyl)piperidin-1-yl)ethan-1-one (CAS 1482565-56-9)
- 5-chloro-3-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 1638768-23-6)
- 2-Chloro-3,3,3-trifluoro-1-(piperidin-1-yl)propan-1-one (CAS 65388-63-8)
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Recommended Standards
- Lenalidomide Impurity 25 (CAS 1218910-61-2)
- Metoclopramide Impurity 96 (CAS 21386-96-9)
- Ziprasidone Impurity 19 (CAS 147124-37-6)
- 4-(5-Chloro-3-fluoropyridin-2-yl)piperazin-2-one (CAS 1125426-55-2)
- 2-((5-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)acetamide (CAS 337354-66-2)
- 5-(2-Bromoethyl)-1,3,4-thiadiazol-2-amine (CAS 511241-17-1)
- Ethyl 3-((tert-butoxycarbonyl)amino)-1-ethyl-1H-pyrrole-2-carboxylate (CAS 2007917-35-1)
- (1R,3r)-3-(3-(trifluoromethyl)phenyl)cyclobutan-1-amine hydrochloride (CAS 1807885-07-9)
- N-(3-Cyano-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1351379-20-8)
- 4-(1-Hydroxyethyl)phenyl acetate (CAS 53744-50-6)
- [6-(4-Amino-phenyl)-4-trifluoromethyl-pyridin-2-yl]-dimethyl-amine (CAS 1311278-01-9)
- 5-(Tert-butyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 505054-57-9)
- 1-Hexanethiol (CAS 111-31-9)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
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