Triamcinolone Acetonide Impurity N1 CAS 2367-73-9
| CAS No. | 2367-73-9 |
| Molecular Formula | C25H35FO8S |
| Molecular Weight | 514.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Triamcinolone Acetonide Impurity N1.
CATO supplies Triamcinolone Acetonide Impurity N1 (CAS 2367-73-9), a pharmacopoeial impurity reference standard (molecular formula C25H35FO8S, MW 514.60 g/mol) used for the identification and quantification of trace impurities in APIs.
Triamcinolone Acetonide Impurity N1 (C25H35FO8S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Triamcinolone Acetonide Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H35FO8S |
| Molecular Weight | 514.60 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Triamcinolone Standards
- Triamcinolone Acetonide Impurity 51 (CAS 2796-78-3)
- Triamcinolone Acetonide Impurity 45 (CAS CATO-C4X-132645)
- Triamcinolone Hexacetonide (CAS 5611-51-8)
- Triamcinolone Acetonide Impurity 37 (CAS 72559-83-2)
- Triamcinolone Acetonide Impurity 47 (CAS 25092-29-9)
- Triamcinolone Acetonide Impurity 42 (CAS CATO-C4X-132642)
- Triamcinolone Diacetate (CAS 67-78-7)
- Triamcinolone Acetonide EP Impurity F (CAS 3870-07-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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