Tucatinib Impurity 4 CAS 1429755-58-7
| CAS No. | 1429755-58-7 |
| Molecular Formula | C26H26N8O2S |
| Molecular Weight | 514.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tucatinib Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Tucatinib Impurity 4 (CAS 1429755-58-7) is a certified pharmaceutical impurity reference standard with the molecular formula C26H26N8O2S and a molecular weight of 514.60 g/mol.
Based on its molecular formula C26H26N8O2S, Tucatinib Impurity 4 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 514.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C26H26N8O2S |
| Molecular Weight | 514.60 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Tucatinib Standards
- Tucatinib Impurity 62 (E-Isomer) (CAS CATO-C4X-260562)
- Tucatinib Impurity 51 (CAS CATO-C4X-260551)
- Tucatinib Impurity 15 (CAS CATO-C4X-260515)
- Tucatinib Impurity 1 (CAS CATO-C4X-26051)
- Tucatinib Impurity 16 (CAS CATO-C4X-260516)
- Tucatinib Impurity 2 (CAS CATO-C4X-26052)
- Tucatinib Impurity 3 (CAS CATO-C4X-26053)
- Tucatinib Impurity 4 (CAS CATO-C4X-26054)
Recommended Standards
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- Fluticasone Propionate CP Impurity X (CAS 1648562-63-3)
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- Quinidine Impurity 3 (CAS 485-65-4)
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- N-(Benzo[d][1,3]dioxol-5-yl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477331-29-6)
- 4-Piperidinyl(2-thienyl)methanone Hydrochloride (CAS 219540-76-8)
- 4-amino-4-methyl-cyclohexanone;hydrochloride (CAS 1262411-95-9)
- Silane, dichlorodimethyl-, polymer with tetrachlorosilane (CAS 51290-26-7)
- (2-Ethoxyethyl)hydrazine Dihydrochloride (CAS 809282-62-0)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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