Prednisolone impurity 63 CAS 23674-85-3
| CAS No. | 23674-85-3 |
| Molecular Formula | C24H31IO6 |
| Molecular Weight | 542.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Prednisolone impurity 63 (CAS 23674-85-3, C24H31IO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Prednisolone impurity 63 (C24H31IO6) contains a flavonoid core, a hydroxyl group, an ether linkage, iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 542.40 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H31IO6 |
| Molecular Weight | 542.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | I-containing |
Related Prednisolone Standards
- Prednisolone metasulfobenzoate (CAS 39175-74-1)
- Prednisolone 21-beta-D-Glucuronide- Sodium Salt (CAS 889463-89-2)
- Prednisolone-21-ß-D-Glucuronide (CAS 512165-95-6)
- Prednisolone 11,21-Diacetate-17-Valerate (CAS 80447-56-9)
- Prednisolone Impurity 17 (CAS CATO-C4X-173717)
- Prednisolone Impurity 51 (CAS 1428883-48-0)
- Prednisolone Impurity 33 (CAS CATO-C4X-173733)
- Prednisolone Impurity 35 (CAS CATO-C4X-173735)
Recommended Standards
- N6-(Trifluoroacetamidohexyl)adenosine 5-Phosphate (CAS 66060-76-2)
- 4-Iodo-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-N-(pyridin-2-yl)benzamide (CAS 155204-23-2)
- N,N-Bis(4-methoxybenzyl)-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)pyridin-2-amine (CAS 2763159-76-6)
- Clevidipine butyrate Impurity 3 (CAS 253597-19-2)
- Lenvatinib Impurity 184 (CAS 2412398-76-4)
- Regorafenib EP Impurity C (CAS 1855006-12-0)
- Roxadustat Impurity 99 (CAS CATO-C4X-221399)
- 3-(Pyridin-2-yl)-3,9-diazaspiro[5.5]undecane hydrochloride (CAS 2155852-37-0)
- 5-Methyl-1-(1-methyl-1h-pyrazol-3-yl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1511044-27-1)
- 2-(3-Iodo-2-oxopropyl)-2,3-dihydro-1h-isoindole-1,3-dione (CAS 35750-03-9)
- 4-(Difluoromethyl)-3-(trifluoromethyl)phenol (CAS 1261606-01-2)
- 2-Methoxy-N-(2-methoxybenzoyl)benzamide (CAS 331440-01-8)
- 1-(4-(Trifluoromethyl)benzyl)pyrrolidine-3-carboxylic acid (CAS 1086380-64-4)
- Macrophage Inhibitory Peptide (CAS 41961-56-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com