Prednisolone Impurity 35 CAS CATO-C4X-173735
| CAS No. | CATO-C4X-173735 |
| Molecular Formula | C23H27BrO7 |
| Molecular Weight | 495.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Prednisolone Impurity 35 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Prednisolone Impurity 35 (CAS CATO-C4X-173735, C23H27BrO7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Prednisolone Impurity 35 (C23H27BrO7) contains a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H27BrO7 |
| Molecular Weight | 495.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Prednisolone Standards
- Prednisolone Impurity 33 (CAS CATO-C4X-173733)
- Prednisolone 21-Acetate 17-Valerate (CAS 72064-79-0)
- Prednisolone Impurity 51 (CAS 1428883-48-0)
- Prednisolone Impurity 42 (CAS 85847-53-6)
- Prednisolone Impurity 44 (CAS 4224-31-1)
- Prednisolone 17-(Ethyl Carbonate) 21-Acetate (CAS 671225-23-3)
- Prednisolone Impurity 17 (CAS CATO-C4X-173717)
- Prednisolone 11,21-Diacetate-17-Valerate (CAS 80447-56-9)
Recommended Standards
- Empagliflozin Impurity N31 (CAS 2452301-12-9)
- Budesonide Impurity 69 (CAS CATO-C4X-138969)
- 1,4,5,8-Tetraamino-2-bromo-6-(3-butylphenoxy)anthracene-9,10-dione (CAS 88602-04-4)
- Budesonide Impurity 62 (CAS CATO-C4X-138962)
- Vonoprazan Impurity 162 (CAS CATO-C4X-1020162)
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- Minoxidil Impurity 32 (CAS CATO-C4X-170032)
- 2-Amino-3-nitrobenzyl Alcohol (CAS 139743-08-1)
- Pyrazolo[1,5-a]pyridin-2-ylmethanamine (CAS 885275-06-9)
- Ethyl 2-{3-[(4-methoxyanilino)carbonyl]-2-pyridinyl}acetate (CAS 338392-14-6)
- Ethyl 6-formyl-2,4-dimethyl-2,4-dihydropyrrolo[3,2-c]pyrazole-5-carboxylate (CAS 2476689-03-7)
- (1S,5R)-5-amino-3,3-difluorocyclohexane-1-carboxylic acid (CAS 882855-60-9)
- Cyclotricatechylene (CAS 1506-76-9)
- Peptide-GMF (CAS CATO-CPTD788469)
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