Febuxostat Impurity 54 CAS 2375033-35-3
| CAS No. | 2375033-35-3 |
| Molecular Formula | C18H20N2O3S |
| Molecular Weight | 344.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Febuxostat Impurity 54 (CAS 2375033-35-3) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20N2O3S and a molecular weight of 344.43 g/mol.
Structurally, Febuxostat Impurity 54 (C18H20N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 344.43 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O3S |
| Molecular Weight | 344.43 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Febuxostat Standards
- Febuxostat Impurity 13 (CAS 160844-75-7)
- Febuxostat Impurity 53 (CAS 2230270-05-8)
- Febuxostat Impurity 55 (CAS CATO-C4X-116255)
- Febuxostat impurity 91 (CAS 1380049-42-2)
- Febuxostat Impurity 99 (CAS CATO-C4X-116299)
- Febuxostat Impurity 43 (CAS 161798-03-4)
- Febuxostat Impurity 60 (CAS 2230270-03-6)
- Febuxostat Impurity 81 (CAS 2375033-31-9)
Recommended Standards
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- Amisulpride Impurity 56 (CAS CATO-C4X-104556)
- Cefazedone impurity 15 (CAS 3004928-24-6)
- Amisulpride Impurity 33 (CAS CATO-C4X-104533)
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- Fluoxetine Impurity 17 (CAS CATO-C4X-135217)
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- 2-(5-Methylthiazol-2-yl)ethan-1-amine (CAS 921145-11-1)
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