4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic Acid CAS 91748-18-4
| CAS No. | 91748-18-4 |
| Molecular Formula | C15H11F3O2 |
| Molecular Weight | 280.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic Acid (C15H11F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic Acid (CAS 91748-18-4), a certified reference material (molecular formula C15H11F3O2, MW 280.24 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11F3O2 |
| Molecular Weight | 280.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 2-Methyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylic acid (CAS 1008773-97-4)
- Methyl 5-(trifluoromethyl)-[1,1'-biphenyl]-3-carboxylate (CAS 101640-74-8)
- 2-Methyl-2-(trifluoromethyl)-[1,1-biphenyl]-4-carboxylic acid (CAS 1140462-04-9)
- 2-(5-(trifluoromethyl)biphenyl-2-yl)acetic acid (CAS 1214346-33-4)
- 2-(3'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetic acid (CAS 1224742-15-7)
- 3'-Methyl-5-(trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261953-10-9)
- MEthyl 3'-(trifluoromethyl)[1,1'-biphenyl]-4-carboxylate (CAS 127783-72-6)
- Methyl 4'-(trifluoromethyl)-[1,1'-biphenyl]-4-carboxylate (CAS 127783-73-7)
Recommended Standards
- 4-(tert-Butyldimethylsilyloxy)methyl-3-methylphenylboronic acid (CAS 2377608-40-5)
- 4,4,4-Trifluoro-3-methylbutan-1-ol (CAS 339-62-8)
- 4-(Benzyloxy)-3-(trifluoromethyl)benzaldehyde (CAS 477980-90-8)
- 4-[(tert-Butyldimethylsilyl)oxy]-2,6-dimethylphenylboronic acid (CAS 858096-68-1)
- (R)-N-(1-(tert-Butyl)piperidin-3-yl)propane-2-sulfonamide (CAS 1349699-68-8)
- 4-Bromo-3-(2-methylpropoxy)aniline (CAS 1691603-91-4)
- 2-(2-Aminophenyl)propan-2-ol (CAS 15833-00-8)
- 5-Bromo-6-methyl-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid (CAS 90767-13-8)
- 1-(2-Methoxyphenyl)-5-oxopyrrolidine-3-carbohydrazide (CAS 1306738-98-6)
- 5-(Trifluoromethoxy)pyrazine-2-carboxylic acid (CAS 1261770-82-4)
- 1-((1,2-Dichloro-2-phenylvinyl)sulfonyl)piperazine (CAS 1432684-08-6)
- 2-(2,5-Dimethoxyphenyl)-4-pentyn-2-ol (CAS 2006278-41-5)
- Furo[2,3-c]isoquinoline (CAS 233-13-6)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
Why CATO?
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