5-Fluoro-1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-indazole CAS 2377610-46-1
| CAS No. | 2377610-46-1 |
| Molecular Formula | C14H18BFN2O2 |
| Molecular Weight | 276.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Fluoro-1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-indazole (C14H18BFN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Fluoro-1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-indazole (CAS 2377610-46-1), molecular formula C14H18BFN2O2 and molecular weight 276.11 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Fluoro-1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-indazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H18BFN2O2 |
| Molecular Weight | 276.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 2-Fluoro-4,6-bis(trifluoromethyl)benzoic acid (CAS 1017777-41-1)
- 4-Fluoro-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 1358574-95-4)
- 6-Fluoro-1-methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 2786863-92-9)
- 6-Fluoro-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 864773-67-1)
- 7-Fluoro-2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-indazole (CAS 2407556-74-3)
- 1-Fluoro-3-(trifluoromethyl)-4-(3,3,3-trifluoropropoxy)benzene (CAS 1779122-36-9)
- 1-Fluoro-2-(trifluoromethyl)-3-(3,3,3-trifluoropropoxy)benzene (CAS 1779122-52-9)
- 1-Fluoro-3-(trifluoromethyl)-2-(3,3,3-trifluoropropoxy)benzene (CAS 1779132-13-6)
Recommended Standards
- 5-(tert-Butyl)-2-iodophenol (CAS 20942-70-5)
- 4-Iodoadamantan-2-one (CAS 34302-17-5)
- 4-(tert-Butyl)-2-iodophenol (CAS 38941-98-9)
- 2-tert-butyl-4-iodophenol (CAS 60803-25-0)
- Cycloheptanone (CAS 502-42-1)
- 2-Chlorobenzenebutanoic acid (CAS 68449-31-0)
- 2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(4-methyl-3-nitrophenyl)acetamide (CAS 337498-67-6)
- 6-(Difluoromethyl)-2,3-dihydrobenzofuran-3-amine (CAS 1273661-35-0)
- Etoricoxib impurity 55 (CAS 646459-40-7)
- Benzoic acid, 4-methyl-, 3-[7-cyano-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indol-1-yl]propyl ester (CAS 1638212-09-5)
- Isoxazole, 4-(chloromethyl)-5-methyl-3-phenyl- (CAS 18718-83-7)
- 3-(5-Mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)-1-(3-(trifluoromethyl)benzyl)pyridin-2(1H)-one (CAS 242471-90-5)
- 1-(2-fluorobenzoyl)piperidin-4-amine (CAS 886498-38-0)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
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