Etoricoxib impurity 55 CAS 646459-40-7
| CAS No. | 646459-40-7 |
| Molecular Formula | C25H22ClN3O3S |
| Molecular Weight | 479.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Etoricoxib impurity 55 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Etoricoxib impurity 55 (CAS 646459-40-7, C25H22ClN3O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C25H22ClN3O3S, Etoricoxib impurity 55 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 479.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Etoricoxib impurity 55 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H22ClN3O3S |
| Molecular Weight | 479.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Etoricoxib Standards
- Etoricoxib Impurity 21 (CAS CATO-C4X-108021)
- Etoricoxib Impurity 33 (CAS 1817735-82-2)
- Etoricoxib Impurity 92 (CAS CATO-C4X-108092)
- Etoricoxib impurity 56 (CAS 646459-51-0)
- Etoricoxib Impurity 12 (CAS CATO-C4X-108012)
- Etoricoxib impurity 01 (CAS 646459-49-6)
- Etoricoxib impurity 53 (CAS 646459-43-0)
- Etoricoxib impurity 54 (CAS 646459-47-4)
Recommended Standards
- N-(4-Chloro-2-methoxy-5-methylphenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477318-74-4)
- 2,7-Dibromo-9-(4-bromophenyl)-9H-carbazole (CAS 1313900-20-7)
- Letaxaban (CAS 870262-90-1)
- 9-(4-Bromophenyl)-3,6-dibromo-9H-carbazole (CAS 73087-83-9)
- Enzalutamide Impurity 24 (CAS 403-24-7)
- Azasetron lmpurity 3 (CAS 5043-81-2)
- Remdesivir Impurity 51 (CAS 2620657-26-1)
- N-methyl-1-(naphthalen-2-yl)methanimine oxide (CAS 41106-04-1)
- (R)-Methyl 2-(((benzyloxy)carbonyl)amino)-2-phenylacetate (CAS 147780-60-7)
- 2-(3,4-dihydro-2H-1-benzopyran-4-yl)-1H-imidazole (CAS 945389-44-6)
- 3,3,3-Trifluoropropanamide (CAS 460-75-3)
- 1-(4-Chloro-5-methylpyrimidin-2-yl)-1,4-diazepane hydrochloride (CAS 1353947-71-3)
- Methyl 3-(aminomethyl)-2-hydroxyhexanoate (CAS 1518185-94-8)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com