Sertraline EP Impurity D CAS 2378750-29-7
| CAS No. | 2378750-29-7 |
| Molecular Formula | 2*C17H18ClN |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sertraline EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Sertraline EP Impurity D (CAS 2378750-29-7) is a certified pharmaceutical impurity reference standard with the molecular formula C17H18ClN and a molecular weight of 271.79 g/mol.
Sertraline EP Impurity D (C17H18ClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | 2*C17H18ClN |
| Molecular Weight | 271.79 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Sertraline Standards
- Sertraline - Impurity C (Freebase) (CAS 107538-91-0)
- Sertraline Acetamide (CAS 1097616-52-8)
- Sertraline Carbamoyl Glucuronide (CAS 119733-44-7)
- Sertraline Impurity 26 (CAS 1198115-10-4（free base）)
- Sertraline RC 11 (CAS 1217630-23-3)
- Sertraline-d3 Hydrochloride (CAS 1217741-83-7)
- Sertraline Impurity 50 HCl (CAS 122873-20-5 (free base))
- Sertraline EP Impurity F Enantiomer (CAS 124379-29-9)
Recommended Standards
- Berberine Impurity 26 (CAS CATO-C4X-219926)
- Dihydralazine EP Impurity A HCl (CAS 649765-80-0 (free base))
- Cefixime Impurity 111 (CAS CATO-C4X-1139111)
- n-(Naphthalen-1-yl)-4-(p-tolyl)thiazol-2-amine (CAS 301236-29-3)
- Etodolac EP Impurity G (CAS 57816-83-8)
- 1-(2-Aminoethyl)-4,4-dimethylcyclohexan-1-ol (CAS 1368353-98-3)
- 4-(2-Chlorobenzyl)piperidin-4-amine dihydrochloride (CAS 1779132-60-3)
- 1-(2-Bromoallyl)-4-isobutylbenzene (CAS 1379352-51-8)
- 2-Cyclobutoxy-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1310404-15-9)
- Anorexigenic Peptide (CAS 69275-10-1)
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