Berberine Impurity 26 CAS CATO-C4X-219926
| CAS No. | CATO-C4X-219926 |
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Berberine Impurity 26 (CAS CATO-C4X-219926, C11H12O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Berberine Impurity 26 (C11H12O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 192.21 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Berberine Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12O3 |
| Molecular Weight | 192.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Berberine Standards
- Berberine Impurity 17 (CAS 6656-13-9)
- Berberine Impurity 6 (CAS 65615-22-7)
- Berberine Impurity 7 (CAS 65615-23-8)
- Berberine Impurity 30 (CAS 2648606-63-5)
- Berberine Impurity 31 (CAS 17388-19-1)
- Berberine Impurity 27 (CAS CATO-C4X-219927)
- Berberine (CAS 2086-83-1)
- Berberine Impurity 34 (CAS CATO-C4X-219934)
Recommended Standards
- Lusutrombopag Impurity 20 (CAS 30279-00-6)
- Siponimod impurity 19 (CAS 2918890-06-7)
- Lusutrombopag Impurity 12 (CAS 2043804-10-8)
- Dotinurad Impurity 98 (CAS CATO-C4X-249498)
- Edoxaban Impurity 113 (CAS CATO-C4X-1063113)
- Flomoxef Impurity 67 (CAS CATO-C4X-138267)
- Adapalene Impurity 4 (CAS 33626-98-1)
- Hydrazinecarbothioamide, 2,2'-[1-(2-ethoxyethyl)-1,2-ethanediylidene]bis[N-[(3-bromo-4-methoxyphenyl)methyl]-, copper complex (CAS 93599-72-5)
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- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
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