Olaparib Impurity 106 CAS 2385199-47-1
| CAS No. | 2385199-47-1 |
| Molecular Formula | C8H3BrFNO |
| Molecular Weight | 228.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Olaparib Impurity 106 (CAS 2385199-47-1), a pharmacopoeial impurity reference standard (molecular formula C8H3BrFNO, MW 228.02 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, Olaparib Impurity 106 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H3BrFNO |
| Molecular Weight | 228.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Olaparib Standards
- Olaparib Impurity 134 (CAS 134435-16-8)
- Olaparib Impurity 39 (CAS 458535-34-7)
- Olaparib Impurity 69 (CAS 1007-16-5)
- Olaparib Impurity 61 (CAS 2558-18-1)
- Olaparib Impurity 30 (CAS 61260-15-9)
- Olaparib Impurity 53 (CAS CATO-C4X-113553)
- Olaparib Impurity 21 (CAS 54769-22-1)
- Olaparib Impurity 66 (CAS 40019-44-1)
Recommended Standards
- 3-Bromo-5-fluoro-4-formylbenzonitrile (CAS 2219379-93-6)
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- (5-Fluoro-2-((2-methoxyethoxy)methyl)phenyl)boronic acid (CAS 1334218-91-5)
- Nicorandil Impurity 16 Nitrate (CAS 4665-58-1)
- Oteseconazole Impurity 3 (CAS CATO-C4X-33373)
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- 2-[3-(2-Hydroxyethyl)-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl]acetic acid (CAS 1353506-06-5)
- (2E)-3-[5-bromo-2-(2-ethoxyethoxy)phenyl]prop-2-enoic acid (CAS 1158092-95-5)
- (3-((Tert-butyldimethylsilyl)oxy)-2,4,6-trifluorophenyl)boronic acid (CAS 1072946-65-6)
- Cyclopentyl(3,5-dichlorophenyl)methanone (CAS 898791-90-7)
- Methyl 5-cyclopropylpicolinate (CAS 1415898-72-4)
- 2,2-Difluoro-2-(5-fluoro-1H-indol-3-yl)ethanamine hydrochloride (CAS 1923082-60-3)
- D-[Ser]11-Semaglutide (CAS CATO-CPTD788629)
Why CATO?
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