Nicorandil Impurity 16 Nitrate CAS 4665-58-1

Description

Compared with other compounds in its class, the molecular weight of 168.09 g/mol gives Nicorandil Impurity 16 Nitrate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Nicorandil Impurity 16 Nitrate (CAS 4665-58-1), a pharmacopoeial impurity reference standard (molecular formula C2H6N2O3NO3, MW 168.09 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Nicorandil Impurity 16 Nitrate (C2H6N2O3NO3) is characterized by an amino-acid-derived structure, an amide group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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