3-Fluoro-8-iodoisoquinoline CAS 2386431-29-2
| CAS No. | 2386431-29-2 |
| Molecular Formula | C9H5FIN |
| Molecular Weight | 273.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Fluoro-8-iodoisoquinoline (CAS 2386431-29-2) is a high-purity analytical reference standard with the molecular formula C9H5FIN and a molecular weight of 273.05 g/mol.
3-Fluoro-8-iodoisoquinoline (C9H5FIN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5FIN |
| Molecular Weight | 273.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 7-Fluoro-1-iodoisoquinoline (CAS 1207448-25-6)
- 5-Fluoro-1-iodoisoquinoline (CAS 1207448-31-4)
- 7-Fluoro-3-iodoquinoline (CAS 1416440-27-1)
- 5-Fluoro-8-iodoquinoline (CAS 1420790-38-0)
- 6-Fluoro-5-iodoquinoline (CAS 1420790-80-2)
- 8-Fluoro-5-iodoquinoline (CAS 1420791-37-2)
- 7-Fluoro-8-iodoquinoline (CAS 1420793-95-8)
- 6-Fluoro-3-iodoquinoline (CAS 1802820-04-7)
Recommended Standards
- 3-Fluoro-7-iodoisoquinoline (CAS 2386041-92-3)
- 8-Fluoro-3-iodoquinoline (CAS 866782-59-4)
- 3-Fluoro-6-iodoisoquinoline (CAS 2386902-79-8)
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