3-Fluoro-6-iodoisoquinoline CAS 2386902-79-8
| CAS No. | 2386902-79-8 |
| Molecular Formula | C9H5FIN |
| Molecular Weight | 273.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Fluoro-6-iodoisoquinoline (CAS 2386902-79-8) is a high-purity analytical reference standard with the molecular formula C9H5FIN and a molecular weight of 273.05 g/mol.
The molecular framework of 3-Fluoro-6-iodoisoquinoline (C9H5FIN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5FIN |
| Molecular Weight | 273.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 7-Fluoro-1-iodoisoquinoline (CAS 1207448-25-6)
- 5-Fluoro-1-iodoisoquinoline (CAS 1207448-31-4)
- 7-Fluoro-3-iodoquinoline (CAS 1416440-27-1)
- 5-Fluoro-8-iodoquinoline (CAS 1420790-38-0)
- 6-Fluoro-5-iodoquinoline (CAS 1420790-80-2)
- 8-Fluoro-5-iodoquinoline (CAS 1420791-37-2)
- 7-Fluoro-8-iodoquinoline (CAS 1420793-95-8)
- 6-Fluoro-3-iodoquinoline (CAS 1802820-04-7)
Recommended Standards
- 3-Fluoro-5-iodoisoquinoline (CAS 2385832-58-4)
- 3-Fluoro-7-iodoisoquinoline (CAS 2386041-92-3)
- 3-Fluoro-4-iodoquinoline (CAS 213772-63-5)
- 3-Fluoro-8-iodoisoquinoline (CAS 2386431-29-2)
- Sodium benzene-1,2,4,5-tetracarboxylate (CAS 148-04-9)
- 5-Amino-2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (CAS 2891867-20-0)
- 1-propylpyrrolidin-3-amine (CAS 1096836-49-5)
- 2,4-Bis(difluoromethoxy)benzaldehyde (CAS 80395-30-8)
- 5-Chloro-2-(phenylsulfanyl)aniline (CAS 4235-20-5)
- 3-(Chloromethyl)quinuclidin-3-ol hydrochloride (CAS 247195-80-8)
- 7-Bromo-5-(pentafluoro-λ6-sulfanyl)benzo[d]oxazole (CAS 1432075-78-9)
- 2-Bromo-6-iodo-3-methylpyridine (CAS 1805025-35-7)
- 7,9-Dihydro-1H-purine-2,6,8(3H)-trione, potassium salt (CAS 7000-30-8)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com