Estradiol Impurity 20 CAS 2398-63-2
| CAS No. | 2398-63-2 |
| Molecular Formula | C21H28O3 |
| Molecular Weight | 328.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Estradiol Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Estradiol Impurity 20 (CAS 2398-63-2) is a certified pharmaceutical impurity reference standard with the molecular formula C21H28O3 and a molecular weight of 328.45 g/mol.
Based on its molecular formula C21H28O3, Estradiol Impurity 20 contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 328.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H28O3 |
| Molecular Weight | 328.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Estradiol Standards
- Estradiol Impurity 52 (CAS CATO-C4X-163652)
- Estradiol Valerate EP Impurity F (CAS 18069-79-9)
- Estradiol Impurity 25 (CAS 4245-41-4)
- Estradiol Impurity 54 (CAS 1743-60-8)
- Estradiol 17beta-sulfate (CAS 3233-69-0)
- ∆9(11)-Estradiol Diacetate (CAS 1169-54-6)
- Δ6,7-Estradiol 3,17-Diacetate (CAS 1971-65-9)
- Estradiol Valerate EP Impurity C (CAS 95959-20-9)
Recommended Standards
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- Levonorgestrel Impurity 41 (CAS CATO-C4X-167741)
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- Latamoxef Impurity 40 (CAS CATO-C4X-179840)
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- CAS 1642185-28-1 (CAS 1642185-28-1)
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- Copper, bis(3-aminocrotonophenonato)- (CAS 26748-05-0)
- 3-Bromo-6-iodopyridazine (CAS 1266675-57-3)
- (Ser(PO?H?)3??·???)-Tau Peptide (379-408) trifluoroacetate salt (CAS 2022956-60-9)
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