Estradiol Valerate EP Impurity C CAS 95959-20-9
| CAS No. | 95959-20-9 |
| Molecular Formula | C23H30O3 |
| Molecular Weight | 354.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Estradiol Valerate EP Impurity C is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Estradiol Valerate EP Impurity C (CAS 95959-20-9), a pharmacopoeial impurity reference standard (molecular formula C23H30O3, MW 354.48 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Estradiol Valerate EP Impurity C (C23H30O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Estradiol Valerate EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H30O3 |
| Molecular Weight | 354.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
Related Estradiol Standards
- Estradiol Valerate EP Impurity G (CAS 1313382-25-0)
- ∆9(11)-Estradiol Diacetate (CAS 1169-54-6)
- Δ6,7-Estradiol 3,17-Diacetate (CAS 1971-65-9)
- Estradiol Impurity 24 (CAS 3434-88-6)
- Estradiol 17-Isovalerate (CAS 869627-83-8)
- Estradiol Valerate EP Impurity B (CAS 21881-45-8)
- 17-Beta-Estradiol 17-Valerate (CAS 979-32-8)
- Estradiol Valerate 17α-Isomer (CAS 182624-54-0)
Recommended Standards
- Altrenogest impurity 14 (CAS 165541-64-0)
- Nilestriol Impurity 3 (CAS CATO-C4X-24513)
- Etretinate (CAS 54350-48-0)
- Cloprostenol Impurity 4 (CAS 23518-25-4)
- Midazolam Impurity 16 (CAS 59467-64-0)
- Tinidazole Impurity 10 (CAS CATO-C4X-193010)
- Fosaprepitant Impurity 16 (CAS 327623-34-7)
- KP372-1 (CAS 1374996-60-7)
- 6-Bromo-1-propylcinnolin-4(1H)-one (CAS 61588-18-9)
- Methyl 2-(o-tolyl)propanoate (CAS 74082-02-3)
- 4-Chloro-3-(5-methylbenzo[d]oxazol-2-yl)aniline (CAS 190436-96-5)
- 1-Methyl-N-((3-methyl-1h-pyrazol-4-yl)methyl)-1h-pyrazol-3-amine (CAS 1182922-38-8)
- (cyclopropylmethyl)(1-phenylethyl)amine (CAS 356539-54-3)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
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