Pomalidomide Impurity 53 CAS 24184-33-6
| CAS No. | 24184-33-6 |
| Molecular Formula | C10H16N4O4 |
| Molecular Weight | 256.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Pomalidomide Impurity 53 (C10H16N4O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 256.26 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Pomalidomide Impurity 53 (CAS 24184-33-6) is a certified pharmaceutical impurity reference standard with the molecular formula C10H16N4O4 and a molecular weight of 256.26 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H16N4O4 |
| Molecular Weight | 256.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 4 |
Related Pomalidomide Standards
- Pomalidomide Impurity 48 (CAS CATO-C4X-135448)
- (S)-Pomalidomide (CAS 202271-89-4)
- Pomalidomide (CAS 19171-19-8)
- (R)-Pomalidomide (CAS 202271-90-7)
- Pomalidomide Impurity 23 (CAS 191732-76-0)
- Pomalidomide Impurity 15 (CAS 5054-59-1)
- Pomalidomide Related Compound 7 (CAS 835616-60-9)
- Pomalidomide Impurity 19 (CAS 39133-20-5)
Recommended Standards
- Diclofenac sodium Impurity 49 (CAS CATO-C4X-105149)
- Clonazepam impurity 16 (CAS CATO-C4X-140316)
- N3-Methylthymidine (CAS 958-74-7)
- Riboflavin EP Impurity A (CAS 1088-56-8)
- Peramivir Impurity 37 (CAS CATO-C4X-183337)
- Omeprazole Impurity 91 (CAS 317807-10-6)
- Gadodiamide Impurity 8 (CAS CATO-C4X-31438)
- 4-Chloro-3,5-dimethylaniline (CAS 51719-61-0)
- 4-Bromo-2-(cyclopentoxy)pyrimidine (CAS 959241-04-4)
- rel-(1R,4R,6S)-1-Methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptane (CAS 13837-75-7)
- Lead phthalate (dibasic) (CAS 17976-43-1)
- 2-phenyl-1-(pyrimidin-2-yl)ethan-1-amine hydrochloride (CAS 1955494-13-9)
- ethyl 5-amino-2-methyl-1-(2,2,2-trifluoroethyl)-1H-imidazole-4-carboxylate (CAS 1285486-92-1)
- Prolactin-Releasing Peptide (1-31) (human) (CAS 215510-22-8)
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