Clonazepam impurity 16 CAS CATO-C4X-140316
| CAS No. | CATO-C4X-140316 |
| Molecular Formula | C14H12N2O3 |
| Molecular Weight | 256.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Clonazepam impurity 16 (CAS CATO-C4X-140316) is a certified pharmaceutical impurity reference standard with the molecular formula C14H12N2O3 and a molecular weight of 256.26 g/mol.
Structurally, Clonazepam impurity 16 (C14H12N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 256.26 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Clonazepam impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12N2O3 |
| Molecular Weight | 256.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Clonazepam Standards
- Clonazepam impurity 18 (CAS 23751-99-7)
- Clonazepam Impurity 22 (CAS 16346-60-4)
- Clonazepam impurity 12 (CAS 2246723-47-5)
- Clonazepam impurity 13 (CAS 106351-41-1)
- Clonazepam impurity 17 (CAS 2246723-40-8)
- Clonazepam impurity 15 (CAS CATO-C4X-140315)
- Clonazepam EP Impurity A (CAS 2011-66-7)
- Clonazepam Impurity 21 (CAS 4306-32-5)
Recommended Standards
- Pomalidomide Impurity 53 (CAS 24184-33-6)
- Riboflavin EP Impurity A (CAS 1088-56-8)
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- Epinephrine /Adrenaline Impurity 127 (CAS CATO-C4X-1849127)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Aprepitant Impurity 20 (CAS 170729-79-0（free base）)
- Tafluprost Impurity 15 (CAS 209861-00-7)
- 6-(2-Chloro-4-fluorophenyl)-6-oxohexanoic acid (CAS 951889-44-4)
- Ethyl 5-chlorobenzo[b]thiophene-2-carboxylate (CAS 13771-67-0)
- Methyl 3-(2-Hydroxy-5-methoxyphenyl)-3-oxopropanoate (CAS 132017-99-3)
- 4-Chloro-3-fluorobenzeneboronic acid pinacol ester, 97% (CAS 627525-83-1)
- [(2,3-Dichlorophenyl)methoxy][(E)-2-[6-methyl-3-(methylsulfanyl)-1,2,4-triazin-5-yl]ethenyl]amine (CAS 338775-73-8)
- 5-Methyl-2-(2-propynyloxy)benzaldehyde (CAS 1087606-32-3)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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