5-(4-(3-Chlorophenyl)piperazine-1-carbonyl)-1-(3,4-dichlorobenzyl)pyridin-2(1H)-one CAS 242472-06-6
| CAS No. | 242472-06-6 |
| Molecular Formula | C23H20Cl3N3O2 |
| Molecular Weight | 476.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-(3-Chlorophenyl)piperazine-1-carbonyl)-1-(3,4-dichlorobenzyl)pyridin-2(1H)-one (CAS 242472-06-6) is a high-purity analytical reference standard with the molecular formula C23H20Cl3N3O2 and a molecular weight of 476.78 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 5-(4-(3-Chlorophenyl)piperazine-1-carbonyl)-1-(3,4-dichlorobenzyl)pyridin-2(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 476.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(4-(3-Chlorophenyl)piperazine-1-carbonyl)-1-(3,4-dichlorobenzyl)pyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H20Cl3N3O2 |
| Molecular Weight | 476.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 4,5-Bis(dodecyloxy)benzene-1,2-diamine (CAS 190435-62-2)
- 10E-382S 242472-05-5 5-[4-(4-chlorophenyl)piperazine-1-carbonyl]-1-[(3,4-dichlorophenyl)methyl]-1,2-dihydropyridin-2-one (CAS 242472-05-5)
- Benzyltris(3-phenylpropyl)silane (CAS 18759-03-0)
- EUK 124 (CAS 186299-35-4)
- 1H-Pyrrole-3-carbohydrazide (CAS 50561-16-5)
- (1s,2r,3r)-1-(2-Phenyl-2h-1,2,3-triazol-4-yl)butane-1,2,3,4-tetraol (CAS 46994-10-9)
- 1-Butyl-4-chloro-1h-pyrazolo[3,4-d]pyrimidine (CAS 937734-78-6)
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