1-(3-Chlorophenyl)-4-[5-(4-fluorophenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]piperazine CAS 865657-93-8
| CAS No. | 865657-93-8 |
| Molecular Formula | C22H17ClF4N6 |
| Molecular Weight | 476.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(3-Chlorophenyl)-4-[5-(4-fluorophenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 1-(3-Chlorophenyl)-4-[5-(4-fluorophenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]piperazine (CAS 865657-93-8), a certified reference material (molecular formula C22H17ClF4N6, MW 476.86 g/mol) for analytical method development and quality control.
The molecular framework of 1-(3-Chlorophenyl)-4-[5-(4-fluorophenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]piperazine (C22H17ClF4N6) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H17ClF4N6 |
| Molecular Weight | 476.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
Related Chlorophenyl Standards
- 3-(5-{[(6z)-2-(2-chlorophenyl)-5-imino-7-oxo-5h,6h,7h-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-ylidene]methyl}furan-2-yl)benzoic acid (CAS 356075-07-5)
- 1-(4-(4-Chlorophenyl)thiazol-2-yl)-N-(4-methylbenzyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321998-53-2)
- 2-(2-{[(4-chlorophenyl)sulfanyl]methyl}-1H-1,3-benzodiazol-1-yl)-N-(2,4-dichlorophenyl)acetamide (CAS 339100-94-6)
- 4-(4-Chlorophenyl)-3-((2,6-dichlorobenzyl)thio)-5-(4-methoxyphenyl)-4H-1,2,4-triazole (CAS 476484-40-9)
- 1-Benzyl-3-((4-chlorophenyl)sulfonyl)-2-imino-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606948-06-5)
- 5-(4-(3-Chlorophenyl)piperazine-1-carbonyl)-1-(3,4-dichlorobenzyl)pyridin-2(1H)-one (CAS 242472-06-6)
- 5-(4-Chlorophenyl)-3-hydroxy-4-(4-isopropoxy-3-methylbenzoyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 371926-28-2)
- Methyl 5-((3-chlorophenyl)carbamoyl)-2-((5,6-dimethyl-2H-pyran-2-yl)(ethoxy)amino)-4-methylthiophene-3-carboxylate (CAS 505096-40-2)
Recommended Standards
- (Z)-Tritriacont-24-en-16-one (CAS 71177-09-8)
- MLN-8054, >98% (HPLC) (CAS 869363-13-3)
- 3-((2-Chloro-6-fluorobenzyl)thio)-5-(((2,6-dichlorobenzyl)thio)methyl)-4-ethyl-4H-1,2,4-triazole (CAS 344271-07-4)
- Temazepam Glucuronide (CAS 3703-53-5)
- (S)-2-phenyl-1-(thiazol-2-yl)ethanamine (CAS 130199-65-4)
- 1-ethyl-3-methyl-5-pyrrolidin-2-yl-1H-pyrazole (CAS 1172976-59-8)
- 5-((2-Fluoro-4-nitrophenyl)amino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione (CAS 1956324-86-9)
- N-Benzyl-3-(2-oxobenzo[d]thiazol-3(2H)-yl)propanamide (CAS 851989-61-2)
- Brexpiprazole Impurity 141 (CAS CATO-C4X-1131141)
- Varenicline Impurity 58 (CAS CATO-C4X-196258)
- dimethyl 2-[4-(trifluoromethyl)anilino]but-2-enedioate (CAS 106509-84-6)
- 2-(((1-(2-Hydroxyethyl)-1H-pyrazol-3-yl)amino)methyl)benzoic acid hydrochloride (CAS 1856021-36-7)
- N-Ethyl-5-(1-ethylpyrrolidin-2-yl)pyridin-2-amine (CAS 1352500-92-5)
- Tirzepatide Impurity 33 (CAS CATO-C4X-324033)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com