1-(4-(4-Chlorophenyl)thiazol-2-yl)-N-(4-methylbenzyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide CAS 321998-53-2
| CAS No. | 321998-53-2 |
| Molecular Formula | C22H16ClF3N4OS |
| Molecular Weight | 476.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-(4-Chlorophenyl)thiazol-2-yl)-N-(4-methylbenzyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-(4-Chlorophenyl)thiazol-2-yl)-N-(4-methylbenzyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 321998-53-2) is a high-purity analytical reference standard with the molecular formula C22H16ClF3N4OS and a molecular weight of 476.90 g/mol.
Structurally, 1-(4-(4-Chlorophenyl)thiazol-2-yl)-N-(4-methylbenzyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide (C22H16ClF3N4OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 476.90 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(4-(4-Chlorophenyl)thiazol-2-yl)-N-(4-methylbenzyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16ClF3N4OS |
| Molecular Weight | 476.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
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- 1-Benzyl-3-((4-chlorophenyl)sulfonyl)-2-imino-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606948-06-5)
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Recommended Standards
- 2,3,5-Tribromo-1,4-dihydroxyanthracene-9,10-dione (CAS 106200-76-4)
- 2-((3-Chloropyrazin-2-yl)(2-phenylquinolin-7-yl)methyl)isoindoline-1,3-dione (CAS 867162-39-8)
- Eltrombopag Impurity 12 (CAS 376592-56-2)
- N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-2,3-diphenylisoxazolidine-5-carbohydrazide (CAS 339102-24-8)
- 5-Methyl-3-(perfluorooctyl)-1H-pyrazole (CAS 243659-12-3)
- Methyl 4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline-7-carboxylate hydrochloride (CAS 1203683-65-1)
- (4-Oxo-3,4-dihydroquinazolin-2-yl)methyl 2H-chromene-3-carboxylate (CAS 1110816-75-5)
- 2-[[[(1,1-Dimethylethoxy)carbonyl]amino]methyl]-propanoic-3,3,3-d3 Acid Phenylmethyl Ester (CAS 375379-70-7)
- 3-(1-Methylpiperidin-2-yl)pyridin-2(1H)-one (CAS 1352515-58-2)
- 3-(4-Fluoro-2-nitrophenoxy)-N-phenylthiophene-2-carboxamide (CAS 303152-68-3)
- 2-(3-Fluoro-5-(trifluoromethyl)thiophen-2-yl)-2-methylpropanoic acid (CAS 950604-93-0)
- (1R,2R)-2-(methylamino)-2,3-dihydro-1H-inden-1-ol (CAS 23671-90-1)
- 1-(3-Fluoro-4-methoxyphenyl)-2-(methylthio)ethan-1-one (CAS 1178931-81-1)
- D-Ala21-Tirzepatide (CAS CATO-CPTD788913)
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