7-chloro-8-methoxy-1H-pyrido[4,3-d]pyrimidine-2,4-dione CAS 2454491-07-5

Purity 97%+In StockPharmaceutical Standards
CAS No.2454491-07-5
Molecular FormulaC8H12ClN3O3
Molecular Weight233.65 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-chloro-8-methoxy-1H-pyrido[4,3-d]pyrimidine-2,4-dione CAS 2454491-07-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 233.65 g/mol gives 7-chloro-8-methoxy-1H-pyrido[4,3-d]pyrimidine-2,4-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

7-chloro-8-methoxy-1H-pyrido[4,3-d]pyrimidine-2,4-dione (CAS 2454491-07-5), molecular formula C8H12ClN3O3 and molecular weight 233.65 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 7-chloro-8-methoxy-1H-pyrido[4,3-d]pyrimidine-2,4-dione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 233.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 7-chloro-8-methoxy-1H-pyrido[4,3-d]pyrimidine-2,4-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H12ClN3O3
Molecular Weight233.65 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2000
Halogen ContentCl-containing
Nitrogen Atoms3

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