2-Amino-5-chloro-3-fluoropyridine CAS 246847-98-3
| CAS No. | 246847-98-3 |
| Molecular Formula | C5H4ClFN2 |
| Molecular Weight | 146.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 146.55 g/mol gives 2-Amino-5-chloro-3-fluoropyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-5-chloro-3-fluoropyridine (CAS 246847-98-3), molecular formula C5H4ClFN2 and molecular weight 146.55 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, fluorine/chlorine substitution, 2-Amino-5-chloro-3-fluoropyridine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 146.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Amino-5-chloro-3-fluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4ClFN2 |
| Molecular Weight | 146.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-3-chloro-5-fluoropyridine (CAS 1214330-79-6)
- 5-Amino-2-chloro-4-fluoropyridine (CAS 1256811-74-1)
- 2-Amino-4-chloro-6-fluoropyridine (CAS 1393547-98-2)
- 3-Amino-2-chloro-5-fluoropyridine (CAS 884495-37-8)
- 4-Amino-2-chloro-5-fluoropyridine (CAS 89510-90-7)
- 2-Amino-4-hydroxy-6-chloro-s-triazine (CAS 38862-29-2)
- 1-Amino(octane-d<SUB>17</SUB>) (CAS 1173022-14-4)
- (2-Amino-1,3-thiazol-4-yl)methanethiol (CAS 105408-34-2)
Recommended Standards
- 5-Chloro-2-fluorophenol (CAS 186589-76-4)
- 2-Chloro-3-fluorophenol (CAS 863870-86-4)
- 5-(Chloromethyl)-2-fluoropyrimidine (CAS 1807147-87-0)
- 2-Chloro-5-fluorophenol (CAS 3827-49-4)
- 5-(4-Aminophenoxy)-2-(furan-2-ylmethyl)isoindoline-1,3-dione (CAS 310451-97-9)
- 4-(4-Ethylphenyl)piperidine (CAS 67765-04-2)
- 4-(2-(4-Methylpiperazin-1-yl)thiazol-4-yl)benzene-1,2-diol (CAS 875471-69-5)
- 2-Hydrazono-3-methyl-2,3-dihydrobenzo[d]thiazole-6-sulfonic acid (CAS 71176-53-9)
- 4-(4-Amino-2-chlorophenoxy)benzonitrile hydrochloride (CAS 1193390-52-1)
- [3,6-Difluoro-2-(methoxymethoxy)phenyl]trimethylsilane (CAS 749230-38-4)
- 1-(3-Fluoro-4-methylphenyl)ethanamine hydrochloride (CAS 2138165-91-8)
- 2-(4-(Difluoromethyl)-3-methoxy-5-methylpyridin-2-yl)acetic acid (CAS 1806959-62-5)
- Methyl 4-(2-((3-cyano-4,6-dimethylpyridin-2-yl)thio)acetamido)benzoate (CAS 332160-99-3)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
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