4-Amino-2-chloro-5-fluoropyridine CAS 89510-90-7
| CAS No. | 89510-90-7 |
| Molecular Formula | C5H4ClFN2 |
| Molecular Weight | 146.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Amino-2-chloro-5-fluoropyridine is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Amino-2-chloro-5-fluoropyridine (CAS 89510-90-7) is a high-purity analytical reference standard with the molecular formula C5H4ClFN2 and a molecular weight of 146.55 g/mol.
Structurally, 4-Amino-2-chloro-5-fluoropyridine (C5H4ClFN2) contains a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 146.55 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Amino-2-chloro-5-fluoropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4ClFN2 |
| Molecular Weight | 146.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-3-chloro-5-fluoropyridine (CAS 1214330-79-6)
- 5-Amino-2-chloro-4-fluoropyridine (CAS 1256811-74-1)
- 2-Amino-4-chloro-6-fluoropyridine (CAS 1393547-98-2)
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- 3-Amino-2-chloro-5-fluoropyridine (CAS 884495-37-8)
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- (2-Amino-1,3-thiazol-4-yl)methanethiol (CAS 105408-34-2)
Recommended Standards
- 3-Chloro-5-fluorophenol (CAS 202982-70-5)
- 4-Chloro-2-fluorophenol (CAS 348-62-9)
- 3-Chloro-4-fluorophenol (CAS 2613-23-2)
- 4-Chloro-5-fluoro-2-methylpyrimidine (CAS 898044-50-3)
- 2-Butoxy-2-oxoethyl butyl phthalate (CAS 85-70-1)
- 3-[2-(1-Acetyl-piperidin-4-yl)-6-methyl-pyrimidin-4-yl]-propionic acid (CAS 1316220-92-4)
- (2S)-2-Amino-N-cyclopropyl-N-((1-methylpiperidin-3-yl)methyl)propanamide (CAS 1354029-27-8)
- Methyl 3-formyl-1-methyl-1H-indole-6-carboxylate (CAS 1160219-36-2)
- tert-Butyl ((3S,5R)-5-(hydroxymethyl)pyrrolidin-3-yl)carbamate hydrochloride (CAS 1865786-36-2)
- Nintedanib Impurity 130 (CAS CATO-C4X-1814130)
- 5H-Pyrrolo[3,4-b]pyridin-7(6H)-one (CAS 1211584-54-1)
- 2-Chloro-1,1,1,6,6,6-hexafluorohexa-2,4-diene (CAS 885276-10-8)
- 13-{[(3-t-Boc)-2,2-Dimethyl-4S-Phenyl-1,3-Oxazolidin-5R-yl]formyl}-7-O-(2,2,2-trichloroethyl)oxy]carbonyl) Baccatin III (CAS 143527-73-5)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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