2-Chloro-5-fluorophenol CAS 3827-49-4

Purity 97%+In StockPharmaceutical Standards
CAS No.3827-49-4
Molecular FormulaC6H4ClFO
Molecular Weight146.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-5-fluorophenol CAS 3827-49-4 chemical structure

Description

The occurrence of 2-Chloro-5-fluorophenol is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Chloro-5-fluorophenol (CAS 3827-49-4), molecular formula C6H4ClFO and molecular weight 146.55 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-5-fluorophenol is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 146.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloro-5-fluorophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H4ClFO
Molecular Weight146.55 g/mol
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Halogen ContentF/Cl-containing

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