Timolol EP Impurity I CAS 2469037-77-0
| CAS No. | 2469037-77-0 |
| Molecular Formula | C11H20N4O3S |
| Molecular Weight | 288.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 288.37 g/mol gives Timolol EP Impurity I distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Timolol EP Impurity I (CAS 2469037-77-0), a pharmacopoeial impurity reference standard (molecular formula C11H20N4O3S, MW 288.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Timolol EP Impurity I is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 288.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Timolol EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H20N4O3S |
| Molecular Weight | 288.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Timolol Standards
- Timolol EP Impurity I (CAS CATO-C4X-149611)
- Timolol Impurity 2 (CAS 75014-26-5)
- Timolol EP Impurity B(Mixture of Enantiomers) (CAS 59697-06-2)
- rac-Timolol (CAS 29023-48-1)
- Timolol EP Impurity B（S-Isomer) (CAS 158636-96-5)
- Timolol EP Impurity H (CAS 158636-97-6)
- Timolol EP Impurity A (CAS 26839-76-9)
- Timolol (CAS 26839-75-8)
Recommended Standards
- N-((2-(Pyrrolidin-1-yl)pyrimidin-4-yl)methyl)thiophene-2-carboxamide (CAS 1797619-79-4)
- (E)-2-((4-ethyl-5-styryl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 478065-59-7)
- (2E)-3-Amino-2-cyano-3-(morpholin-4-yl)-N-phenylprop-2-enethioamide (CAS 158120-88-8)
- 2,4-Dihydro-4-pentyl-1-thioxo[1,2,4]triazolo[4,3-a]quinazolin-5(1H)-one (CAS 757221-12-8)
- Lercanidipine Impurity 34 (CAS 28075-29-8)
- Furosemide Impurity 22 (CAS 82747-56-6)
- Fluralaner Impurity 13 (CAS CATO-C4X-218013)
- 2,6-Dimethyl-3-nitrophenol (CAS 6994-63-4)
- 2-Oxo-2-(2,4,6-trimethoxyphenyl)acetic acid (CAS 62778-01-2)
- 2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxide (CAS 13338-00-6)
- 1,1'-(3,7-Bis(dimethyliminio)nonane-1,9-diyl)bis(4-((3-methylbenzo[d]oxazol-2(3H)-ylidene)methyl)quinolin-1-ium) iodide (CAS 143413-85-8)
- 4-Oxo-N,1-diphenyl-1,4-dihydropyridazine-3-carboxamide (CAS 478063-40-0)
- 2-((1-(2-Fluorophenyl)-1H-tetrazol-5-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 562866-41-5)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com