Furosemide Impurity 22 CAS 82747-56-6
| CAS No. | 82747-56-6 |
| Molecular Formula | C14H12ClNO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Furosemide Impurity 22 (CAS 82747-56-6, C14H12ClNO2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Furosemide Impurity 22 (C14H12ClNO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Furosemide Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12ClNO2 HCl |
| Molecular Weight | 298.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Furosemide Standards
- Furosemide Impurity 64 (CAS 116436-17-0)
- Furosemide-d5 (CAS 1189482-35-6)
- Furosemide Impurity 14 (CAS 133989-65-8)
- Furosemide Impurity 48 Sodium Salt (CAS 133989-65-8（free base）)
- Furosemide Impurity 41 (CAS 137-65-5)
- Furosemide Impurity 33 (CAS 1803102-41-1)
- Furosemide Impurity 32 (CAS 18240-50-1)
- Furosemide Impurity 57 (CAS 19377-82-3)
Recommended Standards
- Pidotimod impurity 6 (CAS 162148-16-5)
- Cholic Acid Impurity 80 (CAS CATO-C4X-116080)
- Tirofiban Impurity 97 (CAS CATO-C4X-125497)
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- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com