Nicardipine Impurity 8 CAS 2469735-68-8
| CAS No. | 2469735-68-8 |
| Molecular Formula | C15H15NO5 |
| Molecular Weight | 289.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Nicardipine Impurity 8 (CAS 2469735-68-8, C15H15NO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Nicardipine Impurity 8 (C15H15NO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Nicardipine Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H15NO5 |
| Molecular Weight | 289.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 1 |
Related Nicardipine Standards
- Nicardipine Cyclohexenone Impurity (CAS 87625-92-1)
- Nicardipine Impurity 24 (CAS 102993-38-4)
- Nicardipine Impurity 40 (CAS CATO-C4X-171040)
- Nicardipine Impurity 41 (CAS CATO-C4X-171041)
- Nicardipine Impurity 72 (CAS CATO-C4X-171072)
- Nicardipine Impurity 5 (CAS 2469555-30-2)
- Nicardipine Impurity 38 (CAS CATO-C4X-171038)
- Nicardipine Impurity 50 (CAS CATO-C4X-171050)
Recommended Standards
- Nintedanib Impurity 124 (CAS CATO-C4X-1814124)
- Nifedipine Impurity 36 (CAS CATO-C4X-141036)
- Nintedanib Nintedanib Impurity 88 (CAS CATO-C4X-181488)
- Emtricitabine impurity 45 (CAS 161683-20-1)
- Diquafosol Impurity N9 (CAS 42155-08-8)
- Finerenone Impurity 154 (CAS CATO-C4X-2880154)
- Letrozole Impurity 37 (CAS 30132-90-2)
- N-(4,5-Dihydrooxazol-2-yl)-4-methylbenzenesulfonamide (CAS 90918-95-9)
- 6-Chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepine (CAS 939759-11-2)
- Rosuvastatin Impurity 107 (CAS 122549-26-2)
- 3,5-Dihydroxyergosta-7,22-dien-6-one (CAS 14858-07-2)
- Vazegepant Impurity 40 (CAS CATO-C4X-320040)
- N-(Pyrrolidin-2-ylmethyl)thiophene-2-sulfonamide hydrochloride (CAS 1261236-10-5)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com