Levofloxacin Impurity 8 CAS 2489671-28-3
| CAS No. | 2489671-28-3 |
| Molecular Formula | C18H20FN3O4 |
| Molecular Weight | 361.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Levofloxacin Impurity 8 (CAS 2489671-28-3, C18H20FN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Levofloxacin Impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 361.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Levofloxacin Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H20FN3O4 |
| Molecular Weight | 361.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Levofloxacin Standards
- Levofloxacin Impurity 1 (CAS 178912-61-3)
- Levofloxacin EP Impurity I (CAS 178912-62-4)
- Levofloxacin R-Isomer（Levofloxacin EP Impurity A） (CAS 100986-86-5)
- Levofloxacin (CAS 100986-85-4)
- Levofloxacin impurity 77 (CAS CATO-C4X-137177)
- Levofloxacin Impurity 80 (CAS CATO-C4X-137180)
- Levofloxacin Impurity 62 (CAS CATO-C4X-137162)
- Levofloxacin Impurity 87 (CAS CATO-C4X-137187)
Recommended Standards
- Topramezone Impurity 1 (CAS CATO-C4X-35031)
- Ofloxacin EP Impurity D (CAS 197291-75-1)
- Ofloxacin (CAS 82419-36-1)
- Gatifloxacin Impurity 3 (CAS 616205-76-6)
- Emtricitabine Impurity 4 (CAS 145397-25-7)
- Cenobamate Impurity 24 (CAS 2297784-40-6)
- Enoxacin Impurity 4 (CAS 87939-21-7)
- Bis(1H-benzo[d]imidazol-1-yl)dimethylsilane (CAS 1858256-89-9)
- ((2R,3S,4S,5S,6R)-6-(4-aminophenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl dihydrogen phosphate (CAS 74160-60-4)
- 1-((4-Ethylphenoxy)methyl)-1h-pyrazol-4-amine (CAS 1004192-76-0)
- 7-Bromo-5-(3,5-difluorophenyl)quinolin-8-ol (CAS 648896-54-2)
- 7-Fluorospiro[indoline-3,3'-pyrrolidin]-2-one (CAS 1552230-93-9)
- 4-Chloro-N-(5-phenyl-1,3,4-oxadiazol-2-yl)butanamide (CAS 65551-65-7)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com