Phenylephrine Impurity 45 CAS 2491-37-4
| CAS No. | 2491-37-4 |
| Molecular Formula | C8H7BrO2 |
| Molecular Weight | 215.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H7BrO2, Phenylephrine Impurity 45 contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 215.04 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Phenylephrine Impurity 45 (CAS 2491-37-4), a pharmacopoeial impurity reference standard (molecular formula C8H7BrO2, MW 215.04 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7BrO2 |
| Molecular Weight | 215.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
Related Phenylephrine Standards
- Phenylephrine Impurity 78 (CAS CATO-C4X-146778)
- Phenylephrine Impurity 89 (CAS CATO-C4X-146789)
- Phenylephrine Impurity 25 (CAS 85299-04-3)
- Phenylephrine Related Compound G (CAS 1094089-46-9)
- Phenylephrine Impurity 68 (CAS CATO-C4X-146768)
- Phenylephrine Impurity 69 (CAS CATO-C4X-146769)
- Phenylephrine Impurity 70 (CAS CATO-C4X-146770)
- Phenylephrine Impurity 33 (CAS CATO-C4X-146733)
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- N1-(7-chloro-4a,8a-dihydroquinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine (CAS 477870-03-4)
- 1-(4-Fluoropiperidin-4-yl)-N,N-dimethylmethanamine hydrochloride (CAS 2306276-53-7)
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