5-Chlorobenzo[d][1,3]dioxole-4-carbaldehyde CAS 249636-63-3
| CAS No. | 249636-63-3 |
| Molecular Formula | C8H5ClO3 |
| Molecular Weight | 184.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-Chlorobenzo[d][1,3]dioxole-4-carbaldehyde (CAS 249636-63-3), a certified reference material (molecular formula C8H5ClO3, MW 184.58 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-Chlorobenzo[d][1,3]dioxole-4-carbaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chlorobenzo[d][1,3]dioxole-4-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClO3 |
| Molecular Weight | 184.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Chlorobenzo Standards
- 4-Chlorobenzo[d][1,3]dioxole-5-carbaldehyde (CAS 110038-91-0)
- 6-Chlorobenzo[d][1,3]dioxole-5-carbaldehyde (CAS 15952-61-1)
- 7-chlorobenzo[d][1,3]dioxole-5-carbaldehyde (CAS 88525-51-3)
- 6-Chlorobenzo[b]thiophen-3(2H)-one (CAS 52038-75-2)
- 7-Chlorobenzo[d]thiazol-5-amine (CAS 196205-26-2)
- 2-Chlorobenzo[d]thiazol-4-amine (CAS 855283-00-0)
- 2-Chlorobenzo[d]thiazol-6-amine (CAS 2406-90-8)
- 4-Chlorobenzo[d]isothiazol-3-amine (CAS 25380-80-7)
Recommended Standards
- 5-Chloro-7-methoxy-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 89581-76-0)
- 6-Amino-5-chlorobenzo[d]oxazol-2(3H)-one (CAS 64037-30-5)
- 5-Chloro-3-hydroxyisobenzofuran-1(3H)-one (CAS 70097-46-0)
- 6-Chloro-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one (CAS 62900-24-7)
- Cephalotin (CAS 153-61-7)
- rac-cis-1-Benzyl-2-methyl-4-(N-propananilido)piperidine-d3 (CAS 1246816-69-2)
- 6-(2-Fluorophenyl)-3-pyridinamine (CAS 160664-94-8)
- Trimethyl({2-[4-(methylamino)phenoxy]ethyl})azanium hydrochloride iodide (CAS 1485426-18-3)
- 2-(3-Methoxyphenyl)hydrazine-1-carbothioamide (CAS 1215296-81-3)
- 2-(Chloromethyl)-4-fluorobenzo[d]oxazole (CAS 139549-22-7)
- 2-Bromo-N-[2-(3,4-dimethoxyphenyl)ethyl]butanamide (CAS 451460-08-5)
- 6,7-dihydro-5H-pyrrolo[3,4-b]pyridine;hydrochloride (CAS 651558-51-9)
- 3-(2,2,2-Trifluoro-1,1-dihydroxyethyl)pyrrolidin-2-one (CAS 1219000-15-3)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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