Carbidopa EP Impurity G CAS 2503-44-8
| CAS No. | 2503-44-8 |
| Molecular Formula | C9H10O3 |
| Molecular Weight | 166.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Carbidopa EP Impurity G (CAS 2503-44-8, C9H10O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C9H10O3, Carbidopa EP Impurity G contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 166.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Carbidopa EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10O3 |
| Molecular Weight | 166.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Carbidopa Standards
- Carbidopa Impurity 36 (CAS 1026009-73-3)
- Carbidopa Impurity 37 (CAS 2409023-90-9)
- Carbidopa Impurity 28 (CAS 319914-20-0)
- Carbidopa Impurity 12 (CAS 53832-94-3)
- Carbidopa Impurity 15 (CAS 579-27-1)
- Carbidopa Impurity 35 (CAS 2104012-68-0)
- Carbidopa EP Impurity A (CAS 555-30-6)
- Carbidopa Impurity 6 (CAS 210576-58-2)
Recommended Standards
- Ipratropium Bromide EP Impurity C (CAS 552-63-6)
- Verapamil EP Impurity G (CAS 120-14-9)
- Methyl DL-Mandelate (CAS 4358-87-6)
- Esmolol Impurity 15 (CAS 501-97-3)
- Mitiglinide Impurity 5 (CAS CATO-C4X-11615)
- Vitamin B6 (Pyridoxine) Impurity 42 (CAS CATO-C4X-187742)
- Aspirin Impurity 14 (CAS 85531-25-5)
- 1-(Furan-2-yl)-2-hydroxy-2-phenylethanone (CAS 36715-43-2)
- 6-Methyl-1,3-dihydrofuro[3,4-c]pyridine-1,7-diol (CAS 17281-92-4)
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