Sulindac EP Impurity C-d3 CAS 250608-66-3
| CAS No. | 250608-66-3 |
| Molecular Formula | - |
| Molecular Weight | 343.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sulindac EP Impurity C-d3 is closely related to deuterium isotope labeling, a steroid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Sulindac EP Impurity C-d3 (CAS 250608-66-3, C20H14D3FO2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to deuterium isotope labeling, a steroid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Sulindac EP Impurity C-d3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 343.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sulindac EP Impurity C-d3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H14D3FO2S |
| Molecular Weight | 343.43 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Sulindac Standards
Recommended Standards
- 5-Methyl-3-(((5-(phenoxymethyl)-1H-1,2,4-triazol-3-yl)methyl)thio)isothiazole-4-carbonitrile (CAS 338418-70-5)
- (Z)-7-((Butyl(methyl)amino)methyl)-6-hydroxy-2-(thiophen-2-ylmethylene)benzofuran-3(2H)-one (CAS 1178096-45-1)
- (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-((((methylthio)methyl)thio)methyl)tetrahydrofuran-3,4-diol (CAS 61839-09-6)
- 2-[(4-ethoxyÂethoxy-3-methyl-2-pyridinylÂ)-methylÂthio]-benzÂimidazole (CAS 121306-13-6)
- Dimetindene EP Impurity D (CAS 1613-23-6)
- Nitrendipine impurity 22 (CAS 89267-43-6)
- Lornoxicam Impurity 6 (CAS 70374-36-6)
- 4,5-Dichloro-3-(dichloromethyl)-1-phenyl-1H-pyrazole (CAS 18767-09-4)
- CP59R9UN62 2146-71-6 Vinyl dodecanoate Dodecanoic acid, ethenyl ester (9CI) Lauric acid, vinyl ester (8CI) Vinyl laurate Dodecanoic acid, ethenyl ester EINECS 218-414-7 NSC 32650 EC 218-414-7 UNII-CP59R9UN62 (CAS 2146-71-6)
- 2-morpholin-4-yl-3-(phenylsulfonyl)propanoic acid (CAS 1087784-41-5)
- (4-Bromo-1-ethyl-1h-pyrazol-3-yl)methanol (CAS 1310379-30-6)
- 3-(5-(2-Chlorophenyl)furan-2-yl)-N-(m-tolyl)acrylamide (CAS 853348-23-9)
- Benzyl benzotriazole-1-carboxylate (CAS 57710-80-2)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
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