Itraconazole Impurity 15 CAS 2508172-07-2
| CAS No. | 2508172-07-2 |
| Molecular Formula | 2*C34H36Cl2N8O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Itraconazole Impurity 15.
CATO supplies Itraconazole Impurity 15 (CAS 2508172-07-2), a pharmacopoeial impurity reference standard (molecular formula C34H36Cl2N8O4, MW 691.61 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Itraconazole Impurity 15 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 691.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Itraconazole Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C34H36Cl2N8O4 |
| Molecular Weight | 691.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Itraconazole Standards
- Itraconazole Impurity 44 (CAS 103661-14-9)
- Itraconazole Impurity 41 (CAS 106461-41-0)
- Itraconazole Impurity 93 (CAS 110762-98-6)
- Itraconazole 2-Oxo Metabolite (CAS 112560-33-5)
- Itraconazole Impurity 38 (CAS 115897-54-6)
- Itraconazole N-Formyl-Ethlene Impurity (CAS 1199350-00-9)
- Itraconazole Impurity 73 (CAS 1199350-02-1)
- Itraconazole-d5(major) (CAS 1217510-38-7)
Recommended Standards
- Perindopril Impurity 13 (CAS 65166-97-4)
- Triamcinolone Acetonide EP Impurity B (CAS 1260149-96-9)
- Ceftriaxone Impurity 13 (CAS CATO-C4X-116313)
- 3-Amino-3-cyclohexylpropan-1-ol hydrochloride (CAS 1173031-67-8)
- 2-(5-Bromothiophen-2-yl)morpholine (CAS 1178409-69-2)
- 2-(4-Amino-2-chloro-5-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805929-59-2)
- 3-Cyclopropyl-2,6-difluorobenzaldehyde (CAS 1609347-18-3)
- 2-Cyclohexylisonicotinamide (CAS 1706441-35-1)
- (4AR,6R,7R,8S,8aR)-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diyl diacetate (CAS 20750-01-0)
- Hexapeptide-10 (CAS 146439-94-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com