3-((2,6-Dichlorobenzyl)sulfonyl)-N-(2,4-difluorophenyl)thiophene-2-carboxamide CAS 251097-08-2

Description

The occurrence of 3-((2,6-Dichlorobenzyl)sulfonyl)-N-(2,4-difluorophenyl)thiophene-2-carboxamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-((2,6-Dichlorobenzyl)sulfonyl)-N-(2,4-difluorophenyl)thiophene-2-carboxamide (CAS 251097-08-2) is a high-purity analytical reference standard with the molecular formula C18H11Cl2F2NO3S2 and a molecular weight of 462.32 g/mol.

The molecular framework of 3-((2,6-Dichlorobenzyl)sulfonyl)-N-(2,4-difluorophenyl)thiophene-2-carboxamide (C18H11Cl2F2NO3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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