4-((2,6-Dichlorobenzyl)oxy)-2-(3-(trifluoromethyl)benzyl)quinazoline CAS 861208-35-7
| CAS No. | 861208-35-7 |
| Molecular Formula | C23H15Cl2F3N2O |
| Molecular Weight | 463.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-((2,6-Dichlorobenzyl)oxy)-2-(3-(trifluoromethyl)benzyl)quinazoline (CAS 861208-35-7), a certified reference material (molecular formula C23H15Cl2F3N2O, MW 463.28 g/mol) for analytical method development and quality control.
Structurally, 4-((2,6-Dichlorobenzyl)oxy)-2-(3-(trifluoromethyl)benzyl)quinazoline (C23H15Cl2F3N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 463.28 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H15Cl2F3N2O |
| Molecular Weight | 463.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorobenzyl Standards
- 1-(2,4-Dichlorobenzyl)-2-oxo-N-(3,4,5-trimethoxyphenyl)-1,2-dihydropyridine-3-carboxamide (CAS 320419-81-6)
- 3-((3,4-Dichlorobenzyl)thio)-N-(3,4-dichlorophenyl)thiophene-2-carboxamide (CAS 251096-88-5)
- 3-((3,4-Dichlorobenzyl)thio)-N-(3,5-dichlorophenyl)thiophene-2-carboxamide (CAS 251096-87-4)
- 3-((2,6-Dichlorobenzyl)sulfonyl)-N-(2,4-difluorophenyl)thiophene-2-carboxamide (CAS 251097-08-2)
- 3-((3,4-Dichlorobenzyl)sulfonyl)-N-(2,4-difluorophenyl)thiophene-2-carboxamide (CAS 251097-76-4)
- 2-((2,4-Dichlorobenzyl)thio)-4-(3,4-dichlorophenoxy)-5-methoxypyrimidine (CAS 866017-30-3)
- 2-((2,6-Dichlorobenzyl)thio)-4-(3,4-dichlorophenoxy)-5-methoxypyrimidine (CAS 338955-98-9)
- 5-(4-((2,4-Dichlorobenzyl)oxy)-3-iodophenyl)-1,3,4-oxadiazol-2-amine (CAS 1706448-72-7)
Recommended Standards
- 1-(2,4-Difluorophenyl)-6-oxo-4-(trifluoromethyl)-N-(4-(trifluoromethyl)phenyl)-1,6-dihydropyridazine-3-carboxamide (CAS 477859-68-0)
- N-(3-chloro-4-methoxybenzyl)-4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxamide (CAS 866137-31-7)
- 4-Chloro-N-[2-(6-chloro-4-trifluoromethyl-pyridine-2-sulfonyl)-ethyl]-benzenesulfonamide (CAS 1311278-04-2)
- Tepotinib impurity 13 (CAS CATO-C4X-337413)
- N-(4-Hydroxybenzyl)acetamide (CAS 34185-04-1)
- 11,11,12,12-Tetracyanonaphtho-2,6-quinodimethane (CAS 6251-01-0)
- 2-Chloro-N-(2-difluoromethoxy-phenyl)-acetamide (CAS 568567-38-4)
- 4-Bromo-6-(methylsulfonyl)pyrimidine (CAS 1367905-95-0)
- Benzyl 3-oxo-1,8-dioxa-4,11-diazaspiro[5.6]dodecane-11-carboxylate (CAS 1251020-98-0)
- (4R)-2-(difluoromethyl)-4-phenyloxazolidine (CAS 1902254-13-0)
- N-(2,4,6-trifluorophenyl)hydrazinecarbothioamide (CAS 206761-92-4)
- 3,3,4,4,4-Pentafluorobutan-1-ol (CAS 54949-74-5)
- N-(4-methylphenyl)hydrazinecarboxamide (CAS 62774-57-6)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com