3-((2,4-Dichlorobenzyl)sulfonyl)-N-(4-fluorophenyl)thiophene-2-carboxamide CAS 251097-60-6
| CAS No. | 251097-60-6 |
| Molecular Formula | C18H12Cl2FNO3S2 |
| Molecular Weight | 444.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-((2,4-Dichlorobenzyl)sulfonyl)-N-(4-fluorophenyl)thiophene-2-carboxamide (C18H12Cl2FNO3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 3-((2,4-Dichlorobenzyl)sulfonyl)-N-(4-fluorophenyl)thiophene-2-carboxamide (CAS 251097-60-6), a certified reference material (molecular formula C18H12Cl2FNO3S2, MW 444.33 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-((2,4-Dichlorobenzyl)sulfonyl)-N-(4-fluorophenyl)thiophene-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12Cl2FNO3S2 |
| Molecular Weight | 444.33 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Dichlorobenzyl Standards
- 1-Benzyl-3-(5-((2,4-dichlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)pyridin-2(1H)-one (CAS 242472-23-7)
- 1-Benzyl-5-(5-((3,4-dichlorobenzyl)thio)-1,3,4-oxadiazol-2-yl)pyridin-2(1H)-one (CAS 477852-96-3)
- 3-((3,4-Dichlorobenzyl)sulfonyl)-N-(4-fluorophenyl)thiophene-2-carboxamide (CAS 251097-77-5)
- (E)-4-((3,4-dichlorobenzyl)oxy)-N'-(3-nitrobenzylidene)benzohydrazide (CAS 303987-29-3)
- 1-(3,4-Dichlorobenzyl)-5-(4-(pyridin-2-yl)piperazine-1-carbonyl)pyridin-2(1H)-one (CAS 860649-40-7)
- 1-(3,4-Dichlorobenzyl)-4-(4-fluorobenzoyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-40-2)
- 1-(3,4-Dichlorobenzyl)-3-((2,6-dichlorobenzyl)oxy)-2-methylpyridin-4(1H)-one (CAS 338965-46-1)
- [4-(3,4-Dichlorobenzyl)homopiperazin-1-yl][2-methyl-6-(trifluoromethyl)pyridin-3-yl]methanone (CAS 646455-88-1)
Recommended Standards
- 1-Benzyl-3-(5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-1,3,4-oxadiazol-2-yl)-1,2-dihydropyridin-2-one (CAS 242472-22-6)
- Bis[2-nitro-4-(trifluoromethyl)phenyl] disulfide (CAS 860-39-9)
- Ethyl 4-(4-chlorophenyl)-2-((3-chloroquinoxalin-2-yl)amino)thiophene-3-carboxylate (CAS 744230-47-5)
- N-debutylhalofantrine (CAS 69756-48-5)
- 2-(2,3-Dihydro-1H-inden-1-ylidene)acetic acid (CAS 4483-48-1)
- N,N-Diethyl-3-[4-(2-methylpropyl)-5-sulfanyl-4H-1,2,4-triazol-3-yl]benzene-1-sulfonamide (CAS 748776-47-8)
- 1-Bromo-4-iodo-5-methoxy-2-(trifluoromethyl)benzene (CAS 2384872-75-5)
- 4-Bromobenzo[b]thiophene-2-carbonitrile (CAS 1312118-13-0)
- 5-Chloro-6-methoxyquinoline-2-carboxylic acid (CAS 1420791-25-8)
- N-[trans-4-[4-(Cyclopropylmethyl)-1-piperazinyl]cyclohexyl]acetamide (CAS 882660-40-4)
- 2,2,2-trifluoro-N-[2-(2-hydroxyethoxy)ethyl]acetamide (CAS 302331-18-6)
- 4-Chlorothiobenzamide (CAS 2521-24-6)
- 4,4,4-trifluoro-2-methylbutan-1-amine hydrochloride (CAS 136564-89-1)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
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