Trazodone Impurity 66 CAS CATO-C4X-177266
| CAS No. | CATO-C4X-177266 |
| Molecular Formula | C13H18Cl2N2 |
| Molecular Weight | 273.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Trazodone Impurity 66 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Trazodone Impurity 66 (CAS CATO-C4X-177266, C13H18Cl2N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Trazodone Impurity 66 (C13H18Cl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Trazodone Impurity 66 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H18Cl2N2 |
| Molecular Weight | 273.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trazodone Standards
- Trazodone impurity 54 (CAS CATO-C4X-177254)
- Trazodone Impurity 73 (CAS 6323-14-4)
- Trazodone Impurity 89 (CAS CATO-C4X-177289)
- Trazodone Impurity N16 (CAS 39577-43-0)
- Trazodone Impurity 103 (CAS CATO-C4X-1772103)
- Trazodone Impurity 36 (CAS CATO-C4X-177236)
- Trazodone impurity 77 (CAS 1799917-53-5)
- Trazodone impurity 64 (CAS CATO-C4X-177264)
Recommended Standards
- n-(2,3-Dichlorobenzyl)-2-(pyrrolidin-1-yl)ethan-1-amine (CAS 827326-59-0)
- Benzyln-butylether (CAS 3459-80-1)
- 3,5-Bis(trifluoromethyl)benzothioamide (CAS 317319-15-6)
- 3-bromobenzophenone (CAS 1016-77-9)
- Itraconazole Impurity 45 (CAS 854372-78-4)
- Relebactam Impurity 76 Monomer (CAS CATO-C4X-214465)
- Lenvatinib Impurity 160 (CAS CATO-C4X-1140160)
- N-Methyl-5-nitro-6-isoquinolinamine (CAS 147293-17-2)
- 1-(Sec-butyl)-4-iodo-1H-pyrazole-5-carboxylic acid (CAS 1354703-69-7)
- N-(pyrimidin-5-ylmethyl)acetamide (CAS 1588441-38-6)
- 2-Amino-1-(3-((isopropyl(methyl)amino)methyl)pyrrolidin-1-yl)ethanone (CAS 1353960-78-7)
- (5-Chloro-2,3-dimethoxyphenyl)methanol (CAS 86232-35-1)
- (3R,4S)-4-fluoro-N,N-dimethylpyrrolidin-3-amine (CAS 960289-62-7)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com