Ribociclib Impurity 17 CAS 2514753-27-4
| CAS No. | 2514753-27-4 |
| Molecular Formula | C23H30N8O2 |
| Molecular Weight | 450.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ribociclib Impurity 17 (CAS 2514753-27-4), a pharmacopoeial impurity reference standard (molecular formula C23H30N8O2, MW 450.54 g/mol) used for the identification and quantification of trace impurities in APIs.
Ribociclib Impurity 17 (C23H30N8O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ribociclib Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H30N8O2 |
| Molecular Weight | 450.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 8 |
Related Ribociclib Standards
- Ribociclib Impurity N1 (CAS 2069953-39-3)
- Ribociclib Impurity 24 (CAS CATO-C4X-310024)
- Ribociclib Impurity 6 (CAS 2470164-21-5)
- Ribociclib Impurity 7 (CAS CATO-C4X-31007)
- Ribociclib Impurity 8 (CAS 2460734-07-8)
- Ribociclib Impurity 27 (CAS CATO-C4X-310027)
- Ribociclib D8 (CAS 2167898-24-8)
- Ribociclib-d6 (CAS 1328934-40-2)
Recommended Standards
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- Probucol Impurity 5 (CAS CATO-C4X-29205)
- Cholic Acid Impurity 1 (CAS 1448-36-8)
- Tetrabenazine Impurity C298 (CAS 100322-43-8)
- 3-(5-Fluoro-2-methoxyphenyl)propanoic acid (CAS 900021-53-6)
- N-(3-(1H-Benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)-2,6-difluorobenzamide (CAS 825615-95-0)
- 4-[(4-chlorophenyl)formamido]butanoic acid (CAS 71455-51-1)
- 2-Acetamidobenzo[d]thiazole-6-sulfonyl chloride (CAS 139601-01-7)
- 4-(Bromomethyl)-2-methyl-1-(trifluoromethyl)benzene (CAS 1261753-84-7)
- Tofacitinib Impurity 82 (CAS 1229041-97-7)
- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com