Ribociclib Impurity 24 CAS CATO-C4X-310024
| CAS No. | CATO-C4X-310024 |
| Molecular Formula | C23H30N8O2 |
| Molecular Weight | 450.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ribociclib Impurity 24 (CAS CATO-C4X-310024, C23H30N8O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ribociclib Impurity 24 (C23H30N8O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 450.54 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ribociclib Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H30N8O2 |
| Molecular Weight | 450.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Ribociclib Standards
- Ribociclib Impurity N1 (CAS 2069953-39-3)
- Ribociclib Impurity 17 (CAS 2514753-27-4)
- Ribociclib Impurity 6 (CAS 2470164-21-5)
- Ribociclib Impurity 7 (CAS CATO-C4X-31007)
- Ribociclib Impurity 8 (CAS 2460734-07-8)
- Ribociclib Impurity 27 (CAS CATO-C4X-310027)
- Ribociclib D8 (CAS 2167898-24-8)
- Ribociclib-d6 (CAS 1328934-40-2)
Recommended Standards
- (9,9-Dihexyl-7-(trimethylsilyl)-9H-fluoren-2-yl)boronic acid (CAS 871468-23-4)
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- (4AR,6S,7R,8S,8aR)-8-(allyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl 4-oxopentanoate (CAS 1186583-16-3)
- Benzyl-PEG6-MS (CAS 1262681-32-2)
- Pinaverium Bromide Impurity 45 (CAS 15766-66-2)
- Mosapride Impurity 60 (CAS 112913-93-6)
- Triclabendazole EP Impurity B (CAS 68828-69-3)
- trans-4-(4-(Cyclopropylmethyl)piperazin-1-yl)cyclohexanamine trihydrochloride (CAS 882660-42-6)
- 1-Azido-2-chlorobenzene (CAS 3296-07-9)
- [6-(4-morpholinyl)-3-pyridinyl]Boronic acid (CAS 904326-93-8)
- Bromosporine (CAS 1619994-69-2)
- 1,3,5-Tribromo-2,4,6-trimethoxybenzene (CAS 105404-90-8)
- 2-amino-N,N-dimethylpyrimidine-5-sulfonamide (CAS 89599-20-2)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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