Trimetazidine EP Impurity E DiHCl CAS 2518359-32-3
| CAS No. | 2518359-32-3 |
| Molecular Formula | C14H22N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Trimetazidine EP Impurity E DiHCl (CAS 2518359-32-3), a pharmacopoeial impurity reference standard (molecular formula C14H22N2O3HCl, MW 302.80 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C14H22N2O3HCl, Trimetazidine EP Impurity E DiHCl contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 302.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H22N2O3 2*HCl |
| Molecular Weight | 302.80 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Trimetazidine Standards
- Trimetazidine EP Impurity A DiHCl (CAS 107049-57-0)
- Trimetazidine EP Impurity G (CAS 110-85-0)
- Trimetazidine Impurity 5 (CAS 1133-49-9)
- Trimetazidine EP Impurity F（Dihydrochloride） (CAS 113698-83-2)
- Trimetazidine-D8 Dihydrochloride (CAS 1219795-37-5)
- Trimetazidine-d8 Dihydrochloride (CAS 1219908-67-4)
- Trimetazidine EP Impurity B (CAS 1257-19-8)
- Trimetazidine Dihydrochloride (CAS 13171-25-0)
Recommended Standards
- Revefenacin Impurity N12 (CAS 1158699-78-5)
- Ciprofloxacin impurity 45 (CAS 93106-58-2)
- Metaraminol Impurity 49 (CAS CATO-C4X-225249)
- 1-(3-Bromophenylsulfonyl)piperidine (CAS 871269-12-4)
- 2-Chloro-4-(3-methoxypropoxy)aniline (CAS 1247204-35-8)
- 5-Bromobenzo[d]isothiazole (CAS 139037-01-7)
- N-tert-Butylbenzenesulfinimidoyl Chloride (CAS 49591-20-0)
- 4'-Ethoxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 118350-18-8)
- Azulene-1-carboxaldehyde (CAS 7206-61-3)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com