1-[(3,4-Dichlorophenyl)methyl]-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile CAS 252058-80-3
| CAS No. | 252058-80-3 |
| Molecular Formula | C19H11Cl2FN2O |
| Molecular Weight | 373.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-[(3,4-Dichlorophenyl)methyl]-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 252058-80-3), molecular formula C19H11Cl2FN2O and molecular weight 373.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-[(3,4-Dichlorophenyl)methyl]-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (C19H11Cl2FN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 1-[(3,4-Dichlorophenyl)methyl]-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H11Cl2FN2O |
| Molecular Weight | 373.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- 1-[(2,4-Dichlorophenyl)methyl]-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 252058-77-8)
- 1-[(2,6-Dichlorophenyl)methyl]-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 252058-78-9)
- 2-(3,4-Dichlorophenyl)-6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 477858-75-6)
- 1-(3,5-Dichlorophenyl)-3-(6-methoxynaphthalen-2-yl)propane-1,3-dione (CAS 924887-13-8)
- 1-[(2,4-Dichlorophenyl)methyl]-6-oxo-N-phenyl-1,6-dihydropyridine-3-carboxamide (CAS 242797-37-1)
- 3-(5-(2,3-Dichlorophenyl)furan-2-yl)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 304896-55-7)
- (3Z)-3-{[(2,4-dichlorophenyl)methoxy]imino}-N-(2,4-difluorophenyl)propanamide (CAS 320417-98-9)
- (3Z)-3-{[(2,6-dichlorophenyl)methoxy]imino}-N-(2,4-difluorophenyl)propanamide (CAS 320418-07-3)
Recommended Standards
- 1-[(2-Chloro-6-fluorophenyl)methyl]-6-(4-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 400089-27-2)
- 1-[(2-Chloro-6-fluorophenyl)methyl]-6-(2-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 252059-16-8)
- 2-[2,4-Bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole (CAS 691868-88-9)
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