Ilaprazole Impurity 165 CAS 253345-81-2
| CAS No. | 253345-81-2 |
| Molecular Formula | C8H11NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ilaprazole Impurity 165 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Ilaprazole Impurity 165 (CAS 253345-81-2, C8H11NO2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ilaprazole Impurity 165 (C8H11NO2HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H11NO2 HCl |
| Molecular Weight | 189.64 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ilaprazole Standards
- Ilaprazole Impurity 166 (CAS 1015057-65-4)
- Ilaprazole Impurity 36 (CAS 1018229-53-2)
- Ilaprazole Impurity N2 (CAS 1018229-57-6)
- Ilaprazole Impurity 40 (CAS 102625-96-7)
- Ilaprazole Impurity 75 (CAS 102625-98-9)
- Ilaprazole-d3 (CAS 1070969-17-3)
- Ilaprazole Dimer Impurity 51 (CAS 1114985-75-9)
- Ilaprazole Impurity 226 (CAS 116419-12-6)
Recommended Standards
- Mivacurium Chloride Impurity 17 (CAS CATO-C4X-137517)
- Pitavastatin Impurity 79 (CAS 2153433-73-7)
- Cefadroxil Impurity 6(Mixture of Diastereomers) (CAS CATO-C4X-12246)
- 4-Chloro-N,N-diethylpyrimidin-2-amine (CAS 71406-62-7)
- 3-(2,5-Dimethylphenyl)-2-oxopropanoic acid (CAS 1247145-65-8)
- 2-(Chloromethyl)-6-(difluoromethyl)-4-iodopyridine-3-carboxaldehyde (CAS 1807103-19-0)
- Celecoxib Impurity 53 (CAS 4392-39-6)
- 1-Ethynyl-2,3,5-trifluorobenzene (CAS 1233513-51-3)
- 2-Bromo-4-(chloromethyl)thiophene (CAS 73919-92-3)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com