Pyrimido[5,4-e][1,2,4]triazine CAS 254-99-9
| CAS No. | 254-99-9 |
| Molecular Formula | C5H3N5 |
| Molecular Weight | 133.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Pyrimido[5,4-e][1,2,4]triazine (CAS 254-99-9), molecular formula C5H3N5 and molecular weight 133.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Pyrimido[5,4-e][1,2,4]triazine (C5H3N5) is characterized by a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Pyrimido[5,4-e][1,2,4]triazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3N5 |
| Molecular Weight | 133.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 5 |
Related Pyrimido Standards
- Pyrimido[4,5-d][1,2,3]triazine (CAS 6133-64-8)
- Pyrimido[5,4-d][1,2,3]triazine (CAS 254-83-1)
- Pyrimido[4,5-c]pyridazine (CAS 254-62-6)
- Pyrimido[4,5-d]pyridazine (CAS 253-88-3)
- Pyrimido[4,5-d]pyrimidine (CAS 254-64-8)
- Pyrimido[5,4-c]pyridazine (CAS 6133-46-6)
- Pyrimido[5,4-d]pyrimidine (CAS 254-82-0)
- 2H-Pyrimido[1,2-a]pyrimidin-2-one (CAS 744255-46-7)
Recommended Standards
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- Abemaciclib Impurity 175 (CAS CATO-C4X-2937175)
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- Tenofovir Disoproxil Impurity 61 (CAS CATO-C4X-107661)
- 4-Fluoro-6-methylpyridin-2-ol (CAS 1227508-66-8)
- N-(p-Tolyl)-1,2,3,4-tetrahydroacridine-9-carboxamide (CAS 74376-51-5)
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