Tenofovir Disoproxil Impurity 61 CAS CATO-C4X-107661
| CAS No. | CATO-C4X-107661 |
| Molecular Formula | C10H17N5O7P2 |
| Molecular Weight | 381.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Tenofovir Disoproxil Impurity 61 (CAS CATO-C4X-107661) is a certified pharmaceutical impurity reference standard with the molecular formula C10H17N5O7P2 and a molecular weight of 381.22 g/mol.
Tenofovir Disoproxil Impurity 61 (C10H17N5O7P2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17N5O7P2 |
| Molecular Weight | 381.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 90 (CAS CATO-C4X-179790)
- Tenofovir alafenamide Impurity 11 (CAS CATO-C4X-179711)
- Tenofovir Alafenamide Impurity 65 (CAS CATO-C4X-179765)
- Tenofovir Alafenamide 64 (CAS CATO-C4X-179764)
- Tenofovir alafenamide Impurity 96 (CAS CATO-C4X-179796)
- Tenofovir Monophosphate (CAS 206646-04-0)
- Tenofovir Alafenamide Impurity 18 (CAS 379270-35-6)
- Tenofovir Alafenamide Impurity 28 (CAS CATO-C4X-179728)
Recommended Standards
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- Imidacloprid Impurity 1 (CAS 105828-41-9)
- Pimavanserin Impurity 2 (CAS 103907-97-7)
- Baloxavir Marboxil Impurity 206 (CAS CATO-C4X-2108206)
- Hydroxychloroquine R-isomer Impurity (CAS 137433-23-9)
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- 2-(4-Chloro-2-methylphenoxy)acetaldehyde (CAS 63354-03-0)
- Ethyl 2-(2-imino-6,7-dihydro-[1,4]dioxino[2',3':4,5]benzo[1,2-d]thiazol-3(2H)-yl)acetate hydrobromide (CAS 2034156-67-5)
- Prasugrel Metabolite M5 (R106583) (CAS 916599-27-4)
- 6-Vinyl-1H-imidazo[4,5-b]pyridine (CAS 1644072-65-0)
- 1-(4-Fluorophenyl)-6-methyl-3-(quinolin-2-ylmethoxy)pyridazin-4(1H)-one (CAS 146824-88-6)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
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