Pitavastatin calcium Impurity 3 CAS 254452-88-5
| CAS No. | 254452-88-5 |
| Molecular Formula | 2*C25H23FNO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 460.54 g/mol gives Pitavastatin calcium Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Pitavastatin calcium Impurity 3 (CAS 254452-88-5), a pharmacopoeial impurity reference standard (molecular formula C25H23FNO4Ca, MW 460.54 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Pitavastatin calcium Impurity 3 (C25H23FNO4Ca) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.5, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 460.54 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pitavastatin calcium Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C25H23FNO4 Ca |
| Molecular Weight | 460.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Pitavastatin Standards
- Pitavastatin Impurity 92 (CAS 1159588-21-2)
- Pitavastatin Impurity 112 (CAS 1187966-91-1)
- Pitavastatin Impurity 90 (CAS 1187966-91-1（free base）)
- Pitavastatin Impurity 51 (CAS 1187966-93-3)
- Pitavastatin Impurity 55 (CAS 1187966-94-4)
- Pitavastatin Impurity 54 (CAS 1187966-95-5)
- Pitavastatin Impurity 40 (CAS 121659-86-7)
- Pitavastatin Impurity 96 (CAS 121660-11-5)
Recommended Standards
- Norepinephrine Impurity 108 (CAS CATO-C4X-1514108)
- Axitinib Impurity 5 (CAS CATO-C4X-10715)
- Milrinone Impurity 25 (CAS CATO-C4X-109125)
- 1-[(4-Nitrophenyl)methyl]-2-oxo-6-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carbonitrile (CAS 252059-85-1)
- 1-(2-Methylphenyl)-1H-pyrazole (CAS 20157-44-2)
- 5-Bromo-4-methyl-3-nitro-1H-pyrazole (CAS 2514952-92-0)
- 1-[1-(4-Fluoro-phenyl)-propyl]-1H-[1,2,3]triazole-4-carboxylic acid (CAS 889939-76-8)
- Perfluoro-3,6-dioxa-4-methyl-7-octene-1-sulfonic acid (CAS 29311-67-9)
- 1-[3-fluoro-4-(oxan-2-ylmethoxy)phenyl]ethan-1-one (CAS 1019529-17-9)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com